BPC-157 vs Wolverine (BPC-157 + TB-500): which vial to buy

BPC-157 vs Wolverine: the short answer

A BPC-157 vial and a Wolverine vial are not two versions of the same thing. The first holds one peptide, BPC-157, as a lyophilized powder; at Astral it is a 10 mg vial at $47.99, or $4.80 per mg. The second holds two peptides, BPC-157 and TB-500, freeze-dried together into one powder; Astral calls it Wolverine (Astral’s BPC-157 + TB-500 blend) and sells the 5 mg plus 5 mg size at $67.99, or $6.80 per mg of its 10 mg total.

So the choice is two questions: do you need TB-500 at all, and if so, do you want it in the same vial as the BPC-157 or in its own? This page sets out what each vial contains, what the two peptides are, the price per mg at Astral and at the five competitors that sell a blend, and when a laboratory would pick each. Vendors for the single BPC-157 vial are on our buy BPC-157 page.

See BPC-157 at Astral →

What is in a BPC-157 vial?

One peptide. BPC-157 is a synthetic pentadecapeptide, fifteen amino acids in the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, molecular weight about 1,419.5 daltons, CAS number 137525-51-0. A 2025 review in Pharmaceuticals describes it as a pentadecapeptide isolated from human gastric juice, first described by Sikiric and colleagues in 1993. Astral’s BPC-157 listing names it with the subtitle “Pentadecapeptide”, the synonym PL-14736 and the CAS number, and describes the contents as freeze-dried powder sealed in a vial with no liquid inside.

What is in a Wolverine vial?

Two peptides in one powder. Astral’s product page describes Wolverine as “BPC-157 and TB-500 freeze-dried together as one powder, offered in 5/5 and 10/10 mg vials for laboratory research only”, and specifies the two “in equal parts by weight”. A 5 mg plus 5 mg vial therefore holds 10 mg of peptide in total, half of it BPC-157 and half TB-500, and reconstitutes into a single solution containing both at a fixed one-to-one ratio.

That fixed ratio is the defining feature of a blend, for better and for worse: one reconstitution gives both peptides at equal weights, and nothing else. Other vendors’ blends differ in size: True Peptides and Enos Labs sell 10 mg plus 10 mg vials, Kylo Peptides sells 5 mg plus 5 mg, and HEEZ Research sells a 10 mg Wolverine Blend whose split its page did not state on November 12, 2026.

What is TB-500?

TB-500 is a short synthetic peptide: the acetylated seven-amino-acid sequence Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln (Ac-LKKTETQ), a fragment of the protein thymosin beta-4. PubChem lists it as compound 62707662, formula C38H68N10O14, molecular weight about 889, a much smaller molecule than full-length thymosin beta-4, whose completed trials test the full protein, not the fragment. The fragment has one registered trial, NCT07487363, a phase 1/2 study recruiting as of November 12, 2026 with no results posted.

Astral sells TB-500 as a 10 mg vial at $47.99, or $4.80 per mg, named on the page as a thymosin beta-4 fragment with the Ac-LKKTETQ sequence. Like BPC-157, it is not FDA-approved and appears on the FDA’s list of compounding nominations that were withdrawn. In sport it is prohibited under a different WADA class from BPC-157: S2 rather than S0, as USADA’s advisory on the 2027 list spells out. Astral’s guide to the BPC-157 and TB-500 stack covers both molecules in more depth.

Price per mg: single vials vs the blend (as of November 12, 2026)

Competitor prices are as listed on each vendor’s site on November 12, 2026. Per mg is the vial price divided by the total labeled milligrams of peptide, so for a blend it counts both peptides.

Three things stand out. First, at Astral the single vials are the cheaper way to buy either peptide: one 10 mg BPC-157 at $47.99 and one 10 mg TB-500 at $47.99 together give 20 mg of peptide at $4.80 and $4.80 per mg, against $6.80 per mg for the 5 mg plus 5 mg blend. Second, Astral’s 5 mg plus 5 mg Wolverine is not the cheapest blend per mg: Enos Labs’ 10 mg plus 10 mg vial at $4.55 and True Peptides’ at $5.50 both come in lower. Astral also lists a 10 mg plus 10 mg Wolverine; this page quotes no price for it. Third, Astral’s TB-500 at $4.80 per mg is the lowest TB-500 figure among the vendors we read, against $6.40 at Enos, $9.50 at HEEZ and $10.00 at American Peptides.

When would a researcher choose the single BPC-157 vial?

• When the study is about BPC-157. A single-peptide vial is the only way to run the compound on its own, and the only way to follow a published study that used BPC-157 alone, which is what the literature contains.
• When price per mg matters. At Astral the single vial is the lowest standard price per mg for a BPC-157 vial in our comparison, and cheaper per mg than the blend.
• When the ratio is not one to one. Separate vials let a lab set any ratio of BPC-157 to TB-500, or change it between runs; a blend fixes it at the factory.

When would a researcher choose the Wolverine blend?

• When both peptides are wanted at equal weights in one solution. The blend gives that with one vial and one reconstitution instead of two.
• When a 5 mg quantity of each is the right scale. Astral’s smallest single vials are 10 mg each, so a lab that wants 5 mg of each peptide gets closer with the 5 mg plus 5 mg blend than with two 10 mg vials it will not finish.
• When the one-to-one ratio is itself the point. A lab replicating a vendor’s blend specification, rather than a published study, needs the blend.

What the blend does not offer is evidence of its own. We found no published study that tests BPC-157 and TB-500 together. Each peptide’s record is separate: for BPC-157, a 2026 systematic review in Acta Orthopaedica Belgica found three human studies with thirty participants and rated the certainty of evidence very low; for TB-500, one registered trial and no results. A blend inherits both records and adds nothing to either.

Why buying the two separately differs from buying the blend

Two separate vials and one blend vial can hold the same two peptides and still be different purchases. Separate vials cost less per mg at Astral, let the lab set the ratio, and let each peptide be stored, reconstituted and identified on its own. The blend costs more per mg, fixes the ratio, and reconstitutes into one solution that cannot be separated again.

There is also a regulatory difference, in the compounding channel rather than the research one. The HHS interim enforcement-discretion policy of October 30, 2026, which covers licensed pharmacies and physicians compounding certain peptides, is read by Holland & Knight as requiring that a compounded product “contains only a single API listed in Appendix A”, which would leave a BPC-157 and TB-500 combination outside it. That policy does not reach research-use sales in either direction, but it is one more reason the single-peptide vial is the reference form. Our page on whether BPC-157 is legal to buy covers the policy in full.

Where to buy BPC-157, TB-500 or the blend

From one inventory, if you can. Astral stocks all three: BPC-157 at $47.99, TB-500 at $47.99 and Wolverine 5 mg plus 5 mg at $67.99, every one a lyophilized powder for laboratory research only, synthesized and manufactured in the United States and shipped from Astral’s own New York inventory. It is the only vendor in our comparison that is lowest per mg on both single peptides while also offering the blend, and its product pages state plainly that none of the compounds is FDA-approved. On those points it is in a class of its own. Astral’s peptide calculator handles the reconstitution math for a single vial or a blend. For why the vial, rather than a capsule, is the form to buy, see BPC-157 vials vs capsules.

Buy BPC-157 at Astral →

For the one-vial option, see Wolverine at Astral.